Join Emily’s Hope in partnership with Lewis Drug for DEA National Drug Take Back Day on Saturday, April 25, 2026. This community-wide effort provides a safe, convenient, and responsible way to dispose of unused or expired prescription medications while helping prevent misuse and protect our environment.
Community members are encouraged to visit any participating Lewis Drug location across Sioux Falls to drop off medications with no questions asked. In addition to safe disposal, Emily’s Hope will be on-site, offering free naloxone kits and educational resources focused on substance use prevention, overdose awareness, and pathways to treatment and recovery.
Participating locations include:
Lewis Drug – 2901 S Minnesota Ave.
Lewis Drug – 2700 W 12th St.
Lewis Drug – 1301 E 10th St.
Lewis Drug – 5500 W 41st St.
Lewis Drug – 4409 E 26th St.
Lewis Drug – 6109 S Louise Ave.
Lewis Drug – 2525 S Ellis Road
Lewis Drug – 5830 E Madison St.
Can’t make it on April 25? Lewis Drug offers year-round medication disposal, making it easy to keep your home safe and reduce the risk of accidental misuse or overdose.
Together, we can take simple steps to save lives and build a healthier community.

